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Gut Health.
Built for Men.

Pharmacist‑formulated supplements that crush bloat, boost energy, and restore performance from the inside out.
  • Supports digestive health & nutrient absorption*
  • Targets bloating, energy crashes & brain fog
  • Clinically-dosed, gut-first formulations
  • No fluff, no gimmicks, just results
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Why Most Men Feel Off (and Don’t Know Why)

Your digestion is wrecked — but it doesn’t show up on a blood test. You feel bloated, sluggish, or gassy, especially after meals.

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You’re tired before the day ends, your workouts aren’t hitting, and your libido has dipped. It's like you're living at 70% power.

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You’ve spent money on random supplements with zero results. You’re tired of chasing influencer hacks and miracle pills.

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Root Causes

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Most men today eat diets loaded with processed foods, low fiber, and cooked meals that lack natural enzymes. Over time, the body becomes less efficient at producing digestive enzymes, especially as we age.

Without enough enzymes, your body can’t fully break down proteins, fats, or carbs — leading to bloating, gas, and poor nutrient absorption. Even high-quality foods can go to waste if your gut can’t digest them properly.

This contributes to fatigue, muscle recovery issues, and stubborn fat gain. Your digestive system is working harder than it should, creating systemic stress. You feel it as brain fog, low energy, and that constant post-meal heaviness.

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Your gut is home to trillions of bacteria — and when the wrong types dominate, everything suffers. Stress, antibiotics, poor diet, and alcohol disrupt the balance between good and bad microbes.

This imbalance (called dysbiosis) weakens the gut lining and promotes inflammation, which spills into energy systems, hormones, and brain function. You may not feel “sick,” but symptoms like mental fog, sluggish digestion, and low drive start showing up.

A compromised microbiome also lowers immunity and impacts testosterone regulation. If you’re always chasing energy with caffeine or feel like your edge is fading, it often starts in your gut.

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Many men are walking around with silent, chronic inflammation driven by poor digestion and gut barrier dysfunction. When your gut lining is compromised — aka “leaky gut” — undigested particles sneak into your bloodstream, triggering immune responses.

Your body stays in a low-level fight mode, which drains energy, clouds thinking, and blunts physical performance. Over time, this creates a hormonal ripple effect, lowering testosterone and increasing cortisol.

You may feel tired, puffy, and less resilient, but traditional bloodwork won’t always catch it. This stealth inflammation is one of the biggest, least diagnosed reasons for declining vitality in men over 40.

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The Solution

ManBiome solves the problem at the root — with pharmacist-formulated, clinically-backed gut support stacks that repair your digestion, restore nutrient absorption, and unlock real energy, performance, and mental clarity.

Makzyme Pro Enzyme Blend

  • Supports athletic performance, enhanced gutmicrobiome, increasedmuscle mass, immune health, reduced cortisol levels, digestive health,cognitive function, and improved allergy symptom.

  • Supports 70% of gut-immunological axis (gut immune system) viaenhanced mucosalimmune response(toll-like receptors), andupregulation of genetic markers associated with macrophage (gut-immune cell) activity.

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Probiotic 40 Billion

  • Supports digestive and immune health via decreased irritablebowelsymptoms, suppression of helicobacter pylori growth (pathogenicbacteria), reduced histamine (reduced allergic response), and reducedgut inflammation.

  • Supports athletic performance via reduction of respiratory tractinfections, reduced muscle damage, improved body composition,reduction lactate induced exercise (muscle burn), and bodycomposition
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Science-Backed Formulas

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Gut-Brain-Hormone Axis Support

Our formulas are engineered to restore communication between your gut, brain, and endocrine system. This triad controls how you digest, focus, and perform — and we target it directly.

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Clinically Validated Ingredients

We only use research-backed ingredients like protease blends, lactobacillus strains, and prebiotics — no proprietary fluff or shady fillers. Everything is dosed based on clinical data.

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Designed for Male Physiology

Male aging and hormone decline follow specific patterns. ManBiome supports male-specific needs for energy, testosterone, and focus through gut-first, hormone-aware formulation.

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Say Hello to your new happy and healthy life

Build your gut. Boost your life.

Core Duo

30 DAY SUPPLY

$85.94 $75.00

Start with EnzyBiome™ and ProBiome™ — your gut reset foundation. Together, they help you break down meals better, boost nutrient absorption, and build a healthy microbial environment.

Core Duo 90 days

90 DAY SUPPLY

$257.82 $244.99

Start with EnzyBiome™ and ProBiome™ — your gut reset foundation. Together, they help you break down meals better, boost nutrient absorption, and build a healthy microbial environment.

Core Duo

MONTHLY SUBSCRIPTION

$75.00 Subscribe and save 10% $67.50

Start with EnzyBiome™ and ProBiome™ — your gut reset foundation. Together, they help you break down meals better, boost nutrient absorption, and build a healthy microbial environment.

Overall Rating For

Man Biome

4.9/5

5 Reviews

Reviews

"After two weeks, my bloating is gone and I’m finally regular again."

Steve, 41

"I’ve tried all kinds of probiotics, but this is the first one that actually worked. My gut feels stable, and I’m way more productive."

Darren, 43

"I started with the Reset Stack and saw results in days. My digestion normalized, I stopped feeling puffy, and I’ve dropped 5 pounds without changing my diet. It’s like my body finally remembered how to work properly."

Luis, 45

"My energy and focus were tanking hard. ManBiome helped me get my edge back — I’m sharper at work and more present at home. This isn’t hype, it’s science that works."

James, 39

"My doctor recommended this, and I felt a huge difference. No more bloating, or random stomach aches."

Kyle, 36

About us

Pharmacist‑Founded. Results‑Driven.

ManBiome™ was born from one pharmacist’s mission to fix the most overlooked health issue in men: gut dysfunction. With over 20 years of clinical experience, we saw how gut issues quietly sabotage energy, hormones, and performance — and how most solutions were fluff or influencer-fueled nonsense.

We built ManBiome for men who want clarity, performance, and control. Our stacks are grounded in science, built for results, and designed to match how real men live and age.

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